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The illegal movements and management of transboundary waste form serious threats to human health and the environment. Hazardous substances released into the air, soil and water due to improper hazardous waste treatment, lead to detrimental consequences affecting generations to come. Several legislative frameworks are in place to ensure the generation of hazardous waste is minimized and to guarantee waste is shipped where it can be appropriately treated in an environmentally sound manner. Dealing with waste in an illegal manner can be very lucrative and even result in serious environmental crime. Promoting compliance through a combination of actions will prevent illegal trafficking of hazardous wastes and eventually protect human health and environment.